Which is a function of ZO-1 proteins?

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Multiple Choice

Which is a function of ZO-1 proteins?

Explanation:
ZO-1 proteins act as tight junction adapter proteins that connect transmembrane tight junction components such as occludin and claudins to the actin cytoskeleton. This linking to actin is essential for assembling and maintaining the junctional belt and for regulating paracellular permeability. Therefore, the function described is mediating actin binding. They are not primarily tumor suppressors, drivers of mitosis, or vesicle transporters, so those options don’t fit as well.

ZO-1 proteins act as tight junction adapter proteins that connect transmembrane tight junction components such as occludin and claudins to the actin cytoskeleton. This linking to actin is essential for assembling and maintaining the junctional belt and for regulating paracellular permeability. Therefore, the function described is mediating actin binding. They are not primarily tumor suppressors, drivers of mitosis, or vesicle transporters, so those options don’t fit as well.

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